![]() ![]() Other cosmetics-associated problems are mutations, allergic reactions, respiratory problems, and several other physiological and reproductive problems. Cosmetic products can prove to be benign, but they can cause cancer when used for a longer duration. Contact allergic dermatitis, the most common type of adverse effect through cosmetic products, has an incidence of 59.2%, caused mainly due to shaving creams, hair dyes, and lipsticks. (2003) reported that the incidence of contact dermatitis is around 3.3% among users of various ingredients of cosmetics. Studies have proven that an average adult uses nine cosmetic products daily. A list of daily use personal care cosmetic products’ ingredients and their related toxic effects are provided in Table 1. However, the US Food and Drug Administration and European Union have introduced guidelines to help consumers to select products based on their sun protection factor (SPF) and protection against ultraviolet (UV) radiation. No major research has been carried out so far regarding cosmetics’ safety and its associated health risks for the chemical ingredients present in them. Those ingredients have been proven to be “penetration enhancers,” which can increase absorption through the skin. contain ingredients that are probably human carcinogens. It has been reported that cosmetic products such as hair dye, shampoo, etc. Earlier studies have suggested that the use of contaminated mascara can even cause blindness. Skin infections can be caused by contaminated hair dyes, body lotions, and sunscreens, particularly when they are applied to dried, cracked, or compromised skin. A majority of the cosmetic products contain water and nutrients that provide utopia for microbial growth and survival. The problems related to cosmetics’ toxicity may be short term and go away if the use of the product is stopped. ![]() The chemical constituents present in cosmetics such as sunscreen, lipsticks, and hair dyes can cause adverse effects in the form of skin allergy, contact dermatitis, or other skin-related diseases. Thus, more focused and dedicated research is warranted to explore the effects of cosmetics on oxidative stress, glycoxidation of biomolecules, and photoproducts accumulation for its total human safety.Ĭosmetics (also referred to as personal care products) are products usually made to cleanse, enhance beauty, prevent skin tanning, increase attractiveness, enrich facial expressions, or altering the appearance without compromising the body’s functions or structure. are performed under bright sunlight conditions. India has tropical weather conditions throughout the year and generally, a majority of human activities such as commerce, agriculture, sports, etc. Sunlight-induced photodegradation and accumulation of cosmetic photoproducts are also a matter of serious concern. Natural antioxidants inhibit oxidative-stress-induced cosmetic toxicity. ![]() ![]() Oxidative stress induces membrane lipid peroxidation, glycoxidation, and protein covalent modifications, resulting in their dysfunction. Cosmetic phototoxicity may include percutaneous absorption, skin irritation, eye irritation, photosensitization, mutagenicity, and genotoxicity. Free-radicals-mediated DNA damage and oxidative stress are common consequences of cosmetic phototoxicity. The effect of light-induced photosensitization of cosmetic products, which results in the production of free radicals through type-I and type-II photosensitization mechanisms. Most cosmetic products have absorption maxima (λmax) in the range of visible light and UV-R. Sunlight has different wavelengths of light, which include UV-A, UV-B, UV-C, and other radiations. Cosmetics are generally applied throughout the face and over the neck region. Cosmetic products include hair dyes, shampoos, skincare, sunscreens, kajal, and other makeup products. Cosmetics, commonly known as ‘makeup’ are products that can enhance the appearance of the human body. ![]()
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